AboutAbout Clinic 45
Serving the Greater Houston area, Clinic 45, a Texas Weight Loss company, is a medical practice and medical spa owned by Joseph E. Sleiman, M.D. Our team of obesity medicine specialists focuses on personalized, medical weight management to help you achieve long-term health and confidence. We specialize in cutting-edge weight loss solutions, including GLP-1 injections, prescription Phentermine, custom diet plans like the Mediterranean and low-carb ketogenic plans, FibroScan liver health evaluations, body composition assessments, and convenient telehealth support. To complement your transformation, our aesthetic center offers anti-aging treatments, including Venus Legacy™ skin tightening, BOTOX®, RF microneedling, and IV hydration.
At a glancePractice Overview
Location8221 Gulf Fwy #400, Houston, TX 77017 ·
View map Business typeWeight loss service · Medical clinic · Medical spa
Treatments offeredB12 shots, Body contouring, Botox, Cellulite Treatment at a Med Spa, Dermal fillers, Dermaplaning, Dysport, Facials, HydraFacial, IPL photofacial +14 more
PaymentCredit cards · Debit cards · Apple Pay / Google Pay
Published pricingTreatment Prices
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Treatment menuTreatments & Specialties
Good to knowAmenities & Accessibility
Accessibility
Wheelchair-accessible entranceAccessible parkingAccessible restroomAccessible seatingPayments
Credit cardsDebit cardsApple Pay / Google PayPatient reviewsWhat Patients Say
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Frequently asked questionsBefore You Book
What treatments does Clinic 45 offer?
B12 shots, Body contouring, Botox, Cellulite Treatment at a Med Spa, Dermal fillers, Dermaplaning, Dysport, Facials, and 16 more, based on their Google profile and website.
Is Clinic 45 good?
It has a 4.8 rating from 1,370 Google reviews, and 1,226 of them are 5 stars.
Where is Clinic 45 located?
8221 Gulf Fwy #400, Houston, TX 77017.
Where this information comes from: the practice's Google Business Profile (rating, hours, categories, amenities), clinic45.com (prices, team, devices, photos) and Google review topics. Last checked October 2026. This listing has not been claimed or verified by the practice.