Peptide Therapy in Knoxville, TN

36 med spas offer peptide therapy in and around Knoxville, compared by Google rating and who does the treatment. New to it? Read our peptide therapy guide.

36Med spas
5.0Top rating
Photo: Brian Stansberry, cropped by Jjtkk, CC BY 3.0

36 Peptide Therapy Providers Near Knoxville

Spas in Knoxville first, then nearby, each ranked by Google rating weighted by number of reviews. No spa paid to be on this page. How we rank

1
Smiley Aesthetics Medical Spa – Botox & Weight Loss Clinic Knoxville⊞ 5 photos
Knoxville · 525 Union Ave · 8.0 mi

Smiley Aesthetics Medical Spa – Botox & Weight Loss Clinic Knoxville

5.0 (559 Google reviews)
CoolSculpting

Smiley Aesthetics Medical Spa in Knoxville, TN offers expert Botox, dermal fillers, Scarlet SRF microneedling, and medical weight loss — led by board-certified physician Dr. Noah Ehinger. Our RN injectors deliver natural, beautiful…

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2
B
Knoxville · 10542 Kingston Pike · 4.9 mi

Beautique Medical Anti-Aging

5.0 (556 Google reviews)
CoolSculptingDiamondGlow

Beautique Medical Anti-Aging is a medical spa in Knoxville. We focus on YOUR goals & use our medical skill & artistry to achieve YOUR goals including: • Non-surgical Facelift using EMFACE • Smooth wrinkles with Botox in Knoxville &…

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3
Restylane Defyne in Knoxville, Tennessee⊞ 4 photos
Knoxville · 10315 Kingston Pike · 4.4 mi

Jessica Ellam Medical Aesthetics

5.0 (480 Google reviews)

Jessica Ellam Medical Aesthetics is a premier aesthetic practice proudly serving the people of TN as well as all over the United States. With a wide range of FDA-approved injectables, advanced medical skincare treatments, and result…

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4
Dermal Fillers | Culture Aesthetics and Wellness | Knoxville, TN⊞ 6 photos
Knoxville · 116 Concord Rd #100 · 6.2 mi

Culture Aesthetics & Wellness

5.0 (290 Google reviews)
DiamondGlowMorpheus8

Culture Aesthetics & Wellness in Knoxville, TN, is your top Medical Spa offering a comprehensive range of services, including injectable treatments, facial treatments, dermal fillers, hair transplants, and wellness services. We are…

Women-ownedOnline bookingLGBTQ+ friendly
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5
Medispa At Choto⊞ 6 photos
Knoxville · 1606 Choto Markets Way · 9.3 mi

Medispa At Choto

5.0 (214 Google reviews)
Morpheus8

Medi Spa at Choto offers a great variety of services! With a mix of medical aesthetics, wellness treatments, and relaxing spa services, it's a one-stop destination for self-care and health. Located in the center of Choto, we proudly…

Women-ownedOnline bookingLGBTQ+ friendly
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6
Fix Head Spa & Beyond⊞ 6 photos
Knoxville · 450 N Cedar Bluff Rd · 2.0 mi

Fix Head Spa & Beyond

5.0 (175 Google reviews)
Alma SopranoSciton Halo

Welcome to our Japanese-inspired head spa, where serenity meets modern self-care. Immerse yourself in a luxurious tranquil oasis offering a unique array of services, including rejuvenating scalp treatments, innovative facials tailored…

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7
18-10932-Murdock-Dr-Suite-102-B-18⊞ 4 photos
Knoxville · 10932 Murdock Dr #102b · 5.3 mi

Vital Hydration

5.0 (109 Google reviews)

Welcome to Vital Hydration, where hydration meets vitality! We understand that life's demands can leave you feeling depleted and fatigued. Whether you've had a long day at work, a rigorous workout, or simply need a boost of energy, our…

Women-owned
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8
Aesthetic Elevation Knoxville⊞ 6 photos
Knoxville · 705 Gate Ln Ste 201 · 2.4 mi

Aesthetic Elevation Knoxville

5.0 (88 Google reviews)
Morpheus8

Medically trained clinicians bringing the greater Knoxville area medical aesthetics services with a personal touch. Featuring advanced anti-aging and rejuvenation from head to toe. Hair restoration and laser hair removal, microneedling,…

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9
Dermal Fillers | Culture Aesthetics and Wellness | Knoxville, TN⊞ 6 photos
Knoxville · 7645 Kingston Pike · 1.1 mi

Culture Aesthetics & Wellness

5.0 (84 Google reviews)
DiamondGlowSciton BBL

Culture Aesthetics & Wellness - West Hills, a trusted medical spa in Knoxville, TN, offers a wide range of services, including injectable treatments, med spa treatments, facial treatments, dermal fillers, hair transplants, and wellness…

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10
RevitalyzeMD⊞ 6 photos
Knoxville · 6504 Deane Hill Dr · 2.6 mi

RevitalyzeMD

4.9 (657 Google reviews)
CoolSculptingFraxel

RevitalyzeMD is a physician founded and operated medical clinic that helps progressive minded men & women feel, look and function amazing at all ages. We are passionate about offering innovative, comprehensive solutions to common…

Women-owned
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More Peptide Therapy Providers Near Knoxville

Sorted by rating × reviews · distance from central Knoxville
#Med spaRatingDistancePrice posted
11Total Hair and Body Medical 4.9 (203)6.0 mi—
12Valencia Medspa 5.0 (46)4.4 mi—
13Ageless Medical Spa 4.9 (151)6.9 mi—
14Breeze Wellness TN 5.0 (44)5.7 mi—
15Simply Ageless Aesthetics, LLC 5.0 (33)13.6 mi—
16The Aesthetic Lounge 5.0 (33)12.2 mi—
17Brooke Nix Medical Aesthetics 5.0 (32)4.8 mi—
18MC Wellness and Aesthetics 5.0 (26)5.3 mi—
19Bridge Aesthetics & Wellness 5.0 (25)3.1 mi—
20West Knox Wellness 5.0 (24)3.1 mi—
21IV4Health & Wellness 5.0 (17)5.0 mi—
22The Skin Wellness Center 4.7 (788)4.2 mi—
23Shea Aesthetic Clinic 5.0 (678)12.5 mi—
24Evolve 865: Jill Larson, APN-B 5.0 (393)13.9 mi—
25The Refinery: Medical Aesthetics and Wellness 5.0 (216)7.0 mi—
26Authentic Medical Aesthetics & Wellness 5.0 (60)13.2 mi—
27HIM & HER Youth and Hydration Clinic 5.0 (28)13.0 mi—
28Curate MedAesthetics - Knoxville 4.8 (976)6.3 mi—
29VibrantMe Wellness Clinic 4.9 (39)6.5 mi—
30Bentley Medical 4.9 (37)6.9 mi—
31Brooke Nix Medical Aesthetics 4.8 (119)13.0 mi—
32Southern Iris Aesthetics 5.0 (14)12.6 mi—
33Studios West Salon Suites 4.8 (59)5.6 mi—
34Adam Eve Medispa 5.0 (11)6.3 mi—
35OptimalJoy Longevity Center 4.6 (33)13.3 mi—
36Botox and Fillers - Shea Aesthetic Clinic—12.5 mi—
From Google reviews

What Knoxville Patients Mention Most

Topics Google pulls from the reviews of the top 10 spas above, counted by mentions.

Friendly staff268RevitalyzeMD
Lip filler100Beautique Medical Anti-Aging
Kind staff88RevitalyzeMD
Relaxing atmosphere72Fix Head Spa & Beyond
Injector71Smiley Aesthetics Medical Spa – Botox & Weight Loss Clinic Knoxville
Comfortable atmosphere62RevitalyzeMD
Relaxing experience50Fix Head Spa & Beyond
Knowledgeable staff38Vital Hydration
Knowledgeable nurse37Beautique Medical Anti-Aging
Iv drip36Vital Hydration
Credentials

Who Does It in Knoxville

Roles named on the websites of the top 10 spas (5 of them list their team).

Physician (MD or DO)2 of 5
Nurse practitioner (NP)4 of 5
Registered nurse (RN)3 of 5
Devices

Devices Knoxville Spas Name

Named by 23 of the 36 spas we checked.

DeviceSpas
Morpheus811
Sciton BBL10
DiamondGlow9
CoolSculpting7
Sciton Halo5
Sciton Moxi4
Emsculpt NEO3
Ultherapy3

Peptide Therapy Near Knoxville by the Numbers

36spas list peptide therapy within 15 miles
25%of the 146 med spas within 15 miles
4.95average Google rating of those spas (35 rated)

36 of the 146 med spas within about 15 miles of Knoxville list peptide therapy on their Google profile or website.

Those 35 rated providers average 4.95 on Google, and 33 hold a 4.8 or higher.

How We Built This Page

Every number here comes from a spa's Google profile or its own website. Nothing is paid for.
Ranked by reviews, not ads. Google rating weighted by how many people left one.
Prices from each spa's own site. Copied from their websites, checked October 2026.
Devices and credentials only when named. If a spa doesn't say, we leave it blank.
Not phone-verified yet. Prices and staff change, so confirm when you book.
Frequently asked questions

Peptide Therapy in Knoxville: Common Questions

What is the best-rated peptide therapy provider in Knoxville?

Smiley Aesthetics Medical Spa – Botox & Weight Loss Clinic Knoxville ranks first on our list, with a 5.0 rating from 559 Google reviews.

We rank by star rating weighted by how many people left one, so a 5.0 from hundreds of patients beats a 5.0 from a handful.

How many med spas offer peptide therapy near Knoxville?

We list 36 within about 15 miles of Knoxville, based on each spa's Google profile and website.

Are peptide therapy providers near Knoxville well rated?

The 35 rated spas within 15 miles that list peptide therapy average 4.95 out of 5 on Google, and 33 hold a 4.8 or higher.

We rank them by rating weighted by how many reviews each has.

What are the med spa rules in Tennessee?

Our Tennessee page sums up what state law and the licensing boards say about who may do med spa treatments, with a source for each rule.

Med spa rules in Tennessee

Which devices do Knoxville med spas use?

23 of the 36 spas we checked name a device on their website.

The most common are Morpheus8 (11), Sciton BBL (10), DiamondGlow (9).

Ask any spa that doesn't say which device it uses.