Botox in O'Fallon, IL

29 med spas offer Botox in and around O'Fallon, compared by Google rating, published prices and who does the treatment. New to it? Read our Botox guide.

29Med spas
4.8Top rating
Photo: Robert Lawton, CC BY-SA 2.5

29 Botox Providers Near O'Fallon

Spas in O'Fallon first, then nearby, each ranked by Google rating weighted by number of reviews. No spa paid to be on this page. How we rank

1
Serene Renewal Medical Spa & Women's Wellness⊞ 2 photos
O'Fallon · 787 Sunset Blvd Ste 200 · 0.4 mi

Serene Renewal Medical Spa & Women's Wellness

4.8 (175 Google reviews)
AviClearCO2RE

Serene Renewal is a unique gynecology practice with medical spa. Now with two spa locations! Bioidentical hormone therapy, IV therapy, Coolsculpting, acne lasers, RF Microneedling, CO2 laser resurfacing of face, Co2re Intima Vaginal…

Women-ownedLatinx-ownedOnline booking
3
Arya Medical Spa⊞ 5 photos
Shiloh · 1185 Fortune Blvd · 1.2 mi

Arya Medical Spa

5.0 (533 Google reviews)
CoolSculptingEmsculpt

WELCOME TO ARYA MEDICAL SPA Arya provides expert facial aesthetic care to help you LIVE BEAUTIFULLY. We offer treatments and products that focus on non-surgical fat reduction, facial rejuvenation, and aging skin.

Women-ownedOnline bookingLGBTQ+ friendly
View ProfileWebsite✓ Takes requests
4
Pure 111 Medical Aesthetics⊞ 5 photos
Fairview Heights · 391 Frank Scott Pkwy E · 2.4 mi

Pure 111 Medical Aesthetics

5.0 (297 Google reviews)
EmsculptEmsculpt NEO

Welcome to Pure 111, your premier center for medical aesthetics and non-surgical cosmetic procedures. Our practice takes a unique boutique spin on the concept of a traditional cosmetic center focusing on upscale accommodations,…

Membership
View ProfileWebsite✓ Takes requests

Only 1 of these spas post Botox prices.

Tell us what you're looking for, and up to 3 spas on this page will send you a quote. You choose which ones.

Get Quotes From 3 Spas
5
Rose MedSpa Team Serves Troy IL and the Metro East Illinois⊞ 6 photos
Troy · 101 E Market St · 10.1 mi

Rose MedSpa and Wellness

5.0 (168 Google reviews)
Morpheus8

Rose MedSpa and Wellness will offer Botox/ neuromodulators, filler, laser hair removal and skin tightening treatments with the highest quality of care and newest technology and training methods. Esthetician services including custom…

Women-ownedOnline bookingMembership
View ProfileWebsite✓ Takes requests
7
Cosmetic treatment in a medical spa setting.⊞ 5 photos
Glen Carbon · 4955 IL-159 #1 · 10.7 mi

MidAmerica Medical Spa

4.9 (215 Google reviews)
CoolSculptingSciton BBL

The medical spa at MidAmerica Plastic Surgery offers non-surgical cosmetic treatments to help make you feel like your best self. Popular options include BOTOX® Cosmetic, dermal fillers, laser hair removal, BBL and HALO™ laser skin…

Online bookingMembership
View ProfileWebsite✓ Takes requests
9
Serene Renewal - Maryville, IL⊞ 2 photos
Maryville · 2236 Vadalabene Dr · 10.3 mi

Serene Renewal - Maryville, IL

5.0 (47 Google reviews)
CoolSculpting

Serene Renewal is a unique gynecology practice with medical spa which focuses on hormone imbalances and the menopause transition. Our medical spa provides tattoo removal, facials, hydrafacials, dermaplaning, Botox, Filler,…

Women-ownedOnline bookingLGBTQ+ friendly
View ProfileWebsite✓ Takes requests
10
I
Glen Carbon · 220 Evergreen Ln A · 13.3 mi

Infinite Vitality

4.9 (138 Google reviews)
Morpheus8

Located in Glen Carbon and serving Edwardsville, IL, Infinite Vitality enhances your natural beauty and overall well-being with personalized, state-of-the-art care. Our expert team offers tailored longevity medicine, bioidentical…

Membership

More Botox Providers Near O'Fallon

Sorted by rating × reviews · distance from central O'Fallon
#Med spaRatingDistancePrice posted
11It's Aesthetically Jess Med Spa & Waxing Suite 5.0 (41)3.1 mi—
12Show Me Care Infusion Therapy 5.0 (41)14.9 mi—
13Laura Marie Esthetics 5.0 (40)10.7 mi—
14Sano Med Spa 4.9 (110)2.9 mi—
15LIVE X MALLORY WILSON 5.0 (36)13.9 mi—
16Quell Aesthetics & Wellness 5.0 (29)10.1 mi—
17EXO Med Spa 4.9 (58)13.9 mi—
18Musick Dermatology & Advanced Clinical Spa 4.8 (801)1.9 mi—
19Lavish Aesthetics 4.9 (42)2.4 mi—
20MidAmerica Plastic Surgery: Ryan Diederich, MD 4.8 (262)10.7 mi—
21Renew Functional Medicine and Anti-aging 5.0 (17)13.5 mi—
22Defined Beauty 5.0 (10)11.7 mi—
23314 Aesthetics 5.0 (10)14.9 mi—
24Quell Headache and Wellness Center - Maryville 4.8 (24)10.1 mi—
25Schweiger Dermatology Group - Glen Carbon 4.7 (796)11.3 mi—
26Bloom Wild Aesthetics and Regenerative Wellness 5.0 (2)2.4 mi$9
27Venus Clinic 5.0 (2)13.4 mi—
28Schaberg Dermatology 4.0 (111)10.5 mi—
29BJC Medical Group Plastic Surgery at Belleville—5.4 mi—
From Google reviews

What O'Fallon Patients Mention Most

Topics Google pulls from the reviews of the top 10 spas above, counted by mentions.

Personable staff42Arya Medical Spa
Lip filler29MidAmerica Medical Spa
Injections21Arya Medical Spa
Caring doctor12Serene Renewal Medical Spa & Women's Wellness
Welcoming atmosphere12Ooh La La Spa, Anti-Aging & Wellness - Medical Spa Edwardsville / Glen Carbon
Iv therapy11MalCole Drip and Beauty Bar
Hrt11Infinite Vitality
Hydrafacial10Pure 111 Medical Aesthetics
Weight loss9Serene Renewal Medical Spa & Women's Wellness
Thorough explanations9Rose MedSpa and Wellness
Credentials

Who Does It in O'Fallon

Roles named on the websites of the top 10 spas (6 of them list their team).

Physician (MD or DO)3 of 6
Nurse practitioner (NP)4 of 6
Registered nurse (RN)3 of 6
Devices

Devices O'Fallon Spas Name

Named by 16 of the 29 spas we checked.

DeviceSpas
CoolSculpting10
Sciton BBL6
Sciton Halo5
Morpheus84
Sciton Moxi3
Secret RF3
Ultherapy3
AviClear2

Botox Near O'Fallon by the Numbers

29spas list Botox within 15 miles
67%of the 43 med spas within 15 miles
4.83average Google rating of those spas (28 rated)

Within a 15-mile drive of O'Fallon, 29 med spas name Botox, which is 67% of the spas in that radius.

The 28 rated spas offering it average 4.83 stars, with 25 at 4.8 or above.

How We Built This Page

Every number here comes from a spa's Google profile or its own website. Nothing is paid for.
Ranked by reviews, not ads. Google rating weighted by how many people left one.
Prices from each spa's own site. Copied from their websites, checked October 2026.
Devices and credentials only when named. If a spa doesn't say, we leave it blank.
Not phone-verified yet. Prices and staff change, so confirm when you book.
Frequently asked questions

Botox in O'Fallon: Common Questions

What is the best-rated Botox provider in O'Fallon?

Serene Renewal Medical Spa & Women's Wellness ranks first on our list, with a 4.8 rating from 175 Google reviews.

We rank by star rating weighted by how many people left one, so a 5.0 from hundreds of patients beats a 5.0 from a handful.

How many med spas offer Botox near O'Fallon?

We list 29 within about 15 miles of O'Fallon, based on each spa's Google profile and website.

Are Botox providers near O'Fallon well rated?

The 28 rated spas within 15 miles that list Botox average 4.83 out of 5 on Google, and 25 hold a 4.8 or higher.

We rank them by rating weighted by how many reviews each has.

What are the med spa rules in Illinois?

Our Illinois page sums up what state law and the licensing boards say about who may do med spa treatments, with a source for each rule.

Med spa rules in Illinois

Which devices do O'Fallon med spas use?

16 of the 29 spas we checked name a device on their website.

The most common are CoolSculpting (10), Sciton BBL (6), Sciton Halo (5).

Ask any spa that doesn't say which device it uses.