Key takeaways
- We found no published per-syringe price for Radiesse, or for hyperdilute Radiesse, when we checked on October 20, 2026.
- ASPS's average fee for non-HA fillers such as Radiesse is $901: fees reported by ASPS member plastic surgeons, not med spa prices.
- "One syringe" is not a fixed volume: FDA has approved several fill sizes, and the current IFU describes a 1.5 mL syringe.
- Hyperdilute Radiesse has one FDA-approved use, décolleté wrinkles, and the studied course was three syringes across three visits.
- ASPS states that health insurance does not cover dermal fillers.
What does Radiesse cost per syringe?
Radiesse is not a hyaluronic acid gel: its instructions for use describe an injectable implant of synthetic calcium hydroxylapatite (CaHA) particles suspended in a gel carrier of sterile water, glycerin and sodium carboxymethylcellulose.
It is supplied in syringes of fixed fill volumes, which is the unit a per-syringe quote turns on.
Those fill volumes are not one number.
FDA supplements approved 0.3 cc and 1.3 cc syringes in 2008, 0.8 cc in 2009 and 3.0 cc in 2011, while the current instructions for use (IFU) describe a 1.5 mL syringe. "One syringe of Radiesse" is therefore not a fixed amount, and two per-syringe quotes can cover different volumes.
What we cannot give you is a verified per-syringe price.
We could not find one published by the manufacturer, ASPS or the consumer cost sources we could read when we checked on October 20, 2026 — and we found no published price for hyperdilute Radiesse either.
This page quotes no per-syringe figure because we could not confirm one, not because the number does not exist.
The figure that is on the record is a category average.
ASPS's dermal-filler cost page lists $901 as the average cost for non-hyaluronic acid fillers, naming Radiesse and Sculptra, alongside $715 for hyaluronic acid fillers and $743 for lip augmentation with filler, per its latest statistics.
These are average fees reported by ASPS member plastic surgeons, not med spa prices: the page does not state the data year, and ASPS does not say whether the fee is per syringe or per procedure.
| Reference point | Figure | What it is |
|---|---|---|
| Syringe in the current IFU | 1.5 mL | The fill volume the instructions for use describe |
| Other approved fill volumes | 0.3, 0.8, 1.3 and 3.0 cc | Approved by FDA supplements, 2008–2011; which sizes are marketed today was not verified |
| ASPS average fee, non-HA fillers | $901 | Radiesse's category; fees reported by ASPS member plastic surgeons; data year not stated |
| ASPS average, HA fillers and lips | $715 / $743 | Same source, same caveats |
When an office quotes per syringe, ask which fill size the price covers and how many syringes the plan assumes. The current IFU describes a 1.5 mL syringe, but FDA records show several fill volumes over the product's history.
How many syringes of Radiesse do you need?
Your total is the per-syringe price times the number of syringes in the plan, and the plan is where the money moves.
We found no label, professional-body or peer-reviewed source that sets a standard number of syringes for a face area, so a "syringes per area" figure you see is an estimate by whoever published it, not a number we could trace to a label, a professional body or a trial.
What the approval record fixes is where Radiesse is approved at all.
FDA's approvals cover moderate to severe facial wrinkles and folds such as nasolabial folds (2006), restoring facial fat loss in people with HIV, volume loss in the back of the hands (2015), jawline contour for the lidocaine version Radiesse (+) (2021) and, diluted 1:2 with saline, décolleté wrinkles in patients 22 and older (2026).
The list has no entry for cheek augmentation, the neck, arms, thighs, abdomen or buttocks, so a Radiesse quote for those areas is pricing an off-label use.
FDA-approved uses
- Moderate to severe facial wrinkles and folds, such as nasolabial folds (2006)
- Facial fat loss in people with HIV
- Volume loss in the back of the hands (2015)
- Jawline contour, Radiesse (+) (2021)
- Décolleté wrinkles, diluted 1:2, ages 22 and older (2026)
Not on the list (off-label)
- Cheek augmentation
- Neck and arms
- Thighs and abdomen
- Buttocks
Ask the office how many syringes the plan assumes and what each one costs before you compare totals.
What the syringes buy — how results build and what treatment involves — is the hub's side of the story: see the Radiesse guide.
Hyaluronidase breaks down hyaluronic acid fillers only, and Radiesse is calcium hydroxylapatite — it is not dissolved the way an HA filler is. The syringe count you agree to is a commitment, which is one more reason to get the plan in writing.
What does hyperdilute Radiesse cost?
Merz describes hyperdiluted Radiesse as the product mixed with a higher volume of saline in a 1:2 ratio so it can be spread more thinly over larger areas.
It has exactly one FDA-approved use: Radiesse diluted 1:2 with sterile saline, injected under the skin with a 22-gauge flexible cannula for décolleté (chest) wrinkles in patients 22 and older, approved on March 31, 2026.
Every other hyperdilute use — the neck, arms, thighs, abdomen, knees and buttocks — is off-label.
The price structure follows the study design.
In the pivotal study (152 subjects at 9 US sites), each treatment was one 1.5 mL syringe of Radiesse diluted with 3.0 mL saline, given on day 1 and again at week 6 and week 12, with optional retreatment at week 36.
That is a series of three syringes across three visits, with a possible fourth — so read a hyperdilute quote as a per-session price, a package for the series, or something else, and ask which.
The décolleté course in the pivotal study
| Visit | When | Product |
|---|---|---|
| Treatment 1 | Day 1 | 1.5 mL Radiesse diluted with 3.0 mL saline |
| Treatment 2 | Week 6 | 1.5 mL Radiesse diluted with 3.0 mL saline |
| Treatment 3 | Week 12 | 1.5 mL Radiesse diluted with 3.0 mL saline |
| Optional retreatment | Week 36 | Offered in the study, not required |
We found no published price for hyperdilute Radiesse in our research.
For body contouring, FDA goes further: it recommends against using any dermal filler to increase the size of the buttocks or breasts, and says these uses are not FDA-approved.
The label says diluted Radiesse must not be injected over or including breast tissue, that more than 18 mL of 1:2-diluted product (6 mL Radiesse plus 12 mL saline) cumulatively over a series of 4 injections has not been studied, and that completion of an indication-specific training program is required for all users treating the décolleté. Large-package quotes for body areas are off-label uses.
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The quote that matters is the one from the offices you contact, and ASPS names what moves filler prices: the injector's expertise and qualifications, the type of procedure, the time and effort required and the geographic location of the office.
The same page states that health insurance does not cover dermal fillers.
FDA's advice sets the floor for who should be behind a quote: the agency says filler injection should be considered a medical procedure, not a cosmetic treatment, and advises choosing a licensed health care provider with dermatology or plastic-surgery experience who is trained in filler injection.
- Does the quote state the price per syringe, and which fill size it covers?
- How many syringes does the plan assume, and for which areas?
- Is the product Radiesse or the lidocaine version, Radiesse (+)?
- For hyperdilute: is the price per session or for the series, and is the plan the on-label décolleté treatment?
- Who will inject, and are they a licensed provider trained in filler injection?
Frequently asked questions
How much does Radiesse cost per syringe?
We could not confirm one.
Our research on October 20, 2026 found no per-syringe price for Radiesse published by the manufacturer, ASPS or the consumer cost sources we could read.
The category figure on the record is ASPS's $901 average fee for non-hyaluronic acid fillers such as Radiesse — fees reported by ASPS member plastic surgeons, with no data year stated and no per-syringe breakdown.
Offices near you can quote per syringe; ask which fill size the price covers.
How many syringes of Radiesse will I need?
There is no standard count: we found no label, professional-body or peer-reviewed source that sets a standard number of syringes per face area.
Radiesse's approved uses are facial wrinkles and folds such as nasolabial folds, facial fat loss in people with HIV, the back of the hands, jawline contour (with the Radiesse (+) version) and diluted décolleté wrinkles.
The provider who examines you sets the count — ask how many syringes the plan assumes.
Is hyperdilute Radiesse approved for the body?
Only the chest.
Its one FDA-approved use is décolleté (chest) wrinkles: Radiesse diluted 1:2 with sterile saline, injected with a cannula, in patients 22 and older, approved on March 31, 2026.
Neck, arms, thighs, abdomen, knees and buttocks uses are off-label.
In the pivotal study the course was three sessions of one 1.5 mL syringe each, on day 1, week 6 and week 12, and we found no published price for the treatment.
Does insurance cover Radiesse?
ASPS states on its dermal-filler cost page that health insurance does not cover dermal fillers, a category that includes Radiesse.
The same page notes filler prices vary with the injector's expertise and qualifications, the type of procedure, the time and effort required and the office's location, so it is worth collecting quotes from more than one office before you book.
Sources
Every number on this page comes from one of these sources and was checked against it.
- Dermal Fillers (Soft Tissue Fillers) · U.S. Food and Drug Administration
- Dermal Fillers Cost · American Society of Plastic Surgeons
- api.fda.gov · U.S. Food and Drug Administration
- radiesse.com · radiesse.com
- Frequently Asked Questions · radiesse.com
Medical disclaimer. MedSpaStandard is for education only and is not medical advice. Talk to a licensed provider about your own health, and check any provider's license with your state board.